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in certain embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as m ox dbqntksplfmgkwnptqk seq id no 2 .
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at boster we strive to provide the best anti-serpina11 antibody by testing all applications on non-spiked tissues and cell lines to ensure that the affinity of the antibody is enough to react to the endogenouse level of the target protein.
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we also subjected these mice to forced treadmill running to assess whether the observed improvement in histopathology conferred by the muscle-specific serpina3n transgene correlated with a functional benefit.
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