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There were no significant differences between olanzapine and divalproex in the rates of symptomatic mania remission over the 47 weeks 56.

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in addition, olanzapine may block the dopamine agonist properties of apomorphine, thereby compromising apomorphine effectiveness.

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olanzapine and other antipsychotic drugs should be used cautiously in patients at risk for aspiration pneumonia.

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notably, our data suggest that olanzapine-induced hyperphagia is the primary cause of weight gain in mice and that olanzapine s effect on food intake is mediated by htr2c.

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in most studies, with or without preventives, olanzapine has resulted in an increased weight gain 7, 8, 18 24 .
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Olanzapine is primarily metabolized by glucuronidation and cytochrome p450 cyp oxidation via cyp1a2 and cyp2d6.

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